Research Projects - D

View our directory of the latest ageing research projects here, complete with the contact details of related researchers and research centres. To view CARDI projects click the button to the right.

Displaying 1 - 4 of 4


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Decision-making regarding medication use in patients with dementia at the end of life

CARDI Involvement

Project Lead

Dr Carole Parsons, Lecturer in Pharmacy Practice, Queens University Belfast

Researchers: 

  • Professor Carmel Hughes, Chair in Primary Care Pharmacy, Queen's University Belfast
  • Professor Peter Passmore, Department of Geriatric Medicine, Queen's University Belfast
  • Dr Denis O'Mahony, University College Cork
  • Dr Stephen Byrne, University College Cork
  • Alzheimer's Society (NI) and the Alzheimer's Society of Ireland (ROI)
Despite the increase in the prevalence and incidence of dementia research into palliative care for patients with advanced dementia is limited. This novel study will seek to evaluate, in Ireland (North and South), the extent to which patient-related factors influence clinical decision-making in respect to medication use in patients with end-stage dementia. 
CARDI grant programme

Diet, retinal microvascular health and cognitive decline and dementia risk

CARDI Involvement

Project Lead

Dr Charlotte Neville
  • Centre for Public Health, QUB

Mentor: Professor Jayne Woodside, QUB

For the CARDI Leadership Programme Dr Charlotte Neville will explore the impact of stress on the neurocognitive and cardiovascular health of older adults in the North and South of Ireland, using data from NICOLA and TILDA. The experience of severe or persistent psychological stress can alter immune mediators, trigger inflammatory processes and increase oxidative stress, damaging brain and cardiovascular health.

CARDI grant programme

Does pain mediate or moderate the protective effects of physical activity on depressive symptoms in older people?

CARDI Involvement

Project Lead

Dr Frank Doyle, Psychology, Royal College of Surgeons in Ireland

Researchers: 

  • Division of Population Health Sciences (Psychology)
    RCSI - Royal College of Surgeons in Ireland
  • Professor Ronan Conroy, Biostatistics, Epidemiology, RCSI
  • Dr Anne Hickey, Psychology, RCSI
  • Dr Caroline Kelleher, Psychology, RCSI
Moderate to high levels of physical activity can reduce the odds of having depression by half or more. Pain has been shown to be associated with a greater risk of depression among older people and also a potential reason for not engaging in physical activity.

Dr Doyle will investigate the extent to which pain interacts with depression and physical activity in Ireland, north and south, which has potentially crucial clinical and policy implications for older people.

CARDI grant programme